There are, of course, situations in which someone has an eating disorder and that is driving their eating habits. Let me tell you, judging them in the “privacy” of your own social circle (be it online or in person) does absolutely nothing to help that person. In fact, it might actively harm them. Genuine concern is not demonstrated by calling people crazy and disapproving of their choices as if shame works.
There’s a lot of truth in that quote above, and in most of the article it’s from.
However, the person writing goes on to how there are no ‘good foods’ or ‘bad foods’, and the need for fat acceptance. There’s of course no thing as a morally ‘good’ or ‘bad’ food, and people should not be judged on their size.
But. There are foods that are good for your health, and foods that are bad for your health. To pretend that mentioning that fact is sizeism, or judgemental, is to hide the reality that certain diets shorten lifespan.
People have every right to chose what diet they have and how they wish to appear, and I would argue against anyone who felt they were better as a person due to their healthier diet. But we cannot ignore the fact that regardless of why someone eats the way they do, often their diet will damage them, and shorten their life. In terms of someone’s health, not all food choices are valid.
As a question I wasn’t able to reblog, but, as far as injecting C3b goes, it makes some sense as a therapy, but really it would have all manner of problems.
C3b is the active form of C3, which we talk about as the ‘central molecule of the complement system’. C3 on it’s own is pretty stable, and…
In an attempt at useful procrastination I submitted an answer to someones Complement question on fyeahanatomy. It’s rushed, and poorly written as a result, but the facts are all there…
After next week I’ll write up a load of new posts, including something clearer on complement.
A study evaluating “pre-exposure prophylaxis,” or PrEP, in women in several African countries has been halted following poor preliminary data. The study provided antiretroviral medications to HIV negative women who are at high risk of contracting HIV.
A similar study previously showed positive results in other high risk groups, so the concept of PrEP is likely to be controversial over the coming years.
Exam tomorrow has = no posts. But this is interesting.
Last year a study found that Truvada (a combination of antiretroviral drugs - Lamivudine and Tenofovir) was effective at preventing HIV in men (it halved the incidence)
But this study, was doing the exact same in women and had to be stopped early as no effect was seen. Is this due to some biological difference in HIV transmission for men and women?
Whilst there is a difference in transmission between men and women, this probably wasn’t the reason why there was no effect seen. Instead, it’s about the risk of HIV in the study.
In this cancelled study, women were in an area with far more HIV and a greater risk. As such, seeing as they were getting their medication for free, they may have been giving/selling a lot of their drugs away (to family members/friends/strangers with money).
The fact that no effect is seen is likely to be that less women were taking the full course of medication, rather than any biological difference between sexes.
Here’s what I’ll be giving a bash at reading in the Lancet today, in some glorious attempt to avoid revision, and revise at the same time. I should be writing more of this lab report up, but obviously Cholera seems far more interesting…
I haven’t read the case report yet, but they’re normally a bit weird and wonderful; for example this (http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(10)61544-9/fulltext) is the story of a lady who managed to spit out screws that had been part of a spinal fixation. Thanks to her inflammatory condition (RA), they’d worked lose, and passed through into her pharynx, for her to spit them up.
Here we have the complement cascade - your inbuilt, automatic, pathogen clearing mechanism.
This set of enzymes have the best named result in all of immunology; The Membrane Attack Complex. This punches a hole in the cell membrane of pathogens/diseased host cells and pumps in enzymes to lyse its targets.
Whilst that’s happening, the fragmented ‘waste’ of complement is attracting WBC’s to the area and making it easier for phagocytosis to take place.
I’m going to make a diagram of all this soon enough.
Hmm, I just went over my cytokines and chemokines flashcards.
Some of them are ever so slightly less than fantastic… They’re still factually correct, but after going through them, you may want to change the prompts. As if you haven’t written them in the first place, it may be a tad confusing as to what they’re asking.
Here we are with two sets now, for cytokines and chemokines.
Cytokines are the messengers that cells use to communicate whilst at (potentially) great distances apart, rather than interacting directly whilst touching. Chemokines are a sub-group of cytokines, as ‘chemoattractant cytokines’. This means that they act as a ‘come over here!’ signal for WBC’s.
So the first link is a set of concepts about cytokines, explaining the structure, function, where they come from, etc. The second link is to something far more dry, but unfortunately necessary for my revision. Cytokines, and their receptors, are generally numbered; so that set is a chunk of the cytokines that I need to remember the ‘name’ of.
Here we go, I’ve had a morning of working my way through lectures and have 4 queued up and ready to go.
This set is all about innate receptor systems, the way that cells of the innate system recognise danger or certain patterns.
As always, these are my revision notes, they may not make sense to all as I’m using them in combination with other techniques. So, sorry if parts seem to be missed out, or sentences seem fragmented, I’m writing them in a way that works for me.
Hopefully I’ll be writing intro posts to these subjects, which should fill in any conceptual blanks that the flashcards miss out.
If you want to get these automatically sent out to your email/rss, there are a set of subscription buttons on flashcard exchange (http://www.flashcardexchange.com/user/view/636745). I had to subscribe myself, simply so I could get the links to share (there seems to be a mega delay in updating my profile page there).
Wow, two written up in one go, I even had to use the queue to stop spamming you all, this feels so little like work it could even just be fancy procrastination. Maybe I’m just trying to make up for a lack of posts though, no matter.
These are an introduction to the innate immune system (the non specific; kill with proteolytic enzymes first and ask questions later system) and it’s tactics.
Right, I’m off to write up some of this lab work. I’ll try to post properly later on.
Schizophrenia (Split personality disorder) is a mental illness characterized by frequent delusions, in-comprehensive thought and speech patterns, and social or occupational dysfunction. Schizophrenia onsets during early adulthood and affects about 0.7% of the global population. The disorder…
The first sentence of this is WRONG. It is NOT a split personality disorder.
maybe whoever wrote it got a bit confused with the whole ‘schiz’ -> split, ‘phrenia’ -> mind ∴ schizophrenia = ‘split mind’ thing?
I used to despise flashcards. They took ages to make, they were really bulky to carry around, and I would ALWAYS lose them (or spill drinks on them, or let them get really crumpled up, or drop them and have to play ‘billion card pick up’)
However, like the geek that I am, I now use an app called Mental Case on my phone, and also it’s laptop equivalent. I get to mix in languages, medicine, immunology and random facts I want to keep.
No matter how many cards I have, they take up the same (physical) space. I can’t lose them, as they’re on my phone, laptop and backed up online. And if I spill drinks on them, well I’ll be more annoyed by frying the electronics rather than losing the cards.
I’m making flashcards of what I’ve learnt this year. Not everything will get a card, some things don’t need them, others are better suited to diagrams and mind maps (or reels of text in some dire circumstances). But a lot will be put down, and I’m going to upload and share them as they’re made.
So, if you’re doing a similar course, or just a bit interested/geeky, then feel free to download them and use them. This is degree level stuff, but not too taxing. At the end of them you’d probably know more immunology than an average clinician.
They’re saved as text. But I could also upload them as images, if anyone was particularly keen on that option.
So here’s set one of loads. Basic (pretty basic) intro to the cells and anatomy of the immune system. There’re a few acronyms, but nothing too confusing (WBCs = White Blood Cells, APCs = Antigen Presenting Cells, DCs = Dendritic Cells, Th = T helper… I think that’s all in those ones)
blah disclaimer blah - all of these are made by someone with no degree in the subject (yet, wait til this summer) - there may be mistakes, and don’t get too annoyed if you put something wrong in your exams as a result, just remember that I’ll have made the same mistake in my exams. There’s nothing in these that would change medical advice, but if later posts do, don’t let some anonymous internet user give you medical advice (unless they’re cranquis, but even then, chat to another doctor). For all you know I’m some 12 year old making up facts as they go along (i’m not, but still)
oh, and if you do see a mistake, let me know. and if you’ve questions, please ask, it’ll help me just as much (in fact - probably more- aren’t I selfish like that) in explaining, as it could help you.